Directory

Digital Health startup ecosystem

We track 49 organisations in this sector across 6+ countries.

49 entries.

33East

Nicosia, Cyprus · Venture Capital

33East was founded by Demetrios Zoppos and Yiannis Eftychiou and selected by the European Investment Fund in 2023 as Cyprus's first EIF-backed venture capital fund. It closed a €26 million debut fund in January 2025, anchored by the Cyprus Equity Fund (NRRP) and private investors including the Bank of Cyprus. The fund targets pre-seed and seed-stage startups with a Cyprus connection, writing cheques of €100K–€1M across enterprise software, fintech, gaming, marketplaces, logistics, digital health, and climate tech. First portfolio companies include Electryone AI, an AI-powered renewable-energy management platform.

Aerska

Dublin, Ireland · Startup

Aerska is a Dublin-based RNA medicines biotech company that uses proprietary brain shuttle technology to overcome the blood-brain barrier and deliver RNAi therapies for neurological diseases such as Alzheimer's and Parkinson's. Founded in 2025 by Jack O'Meara, Dave Hardwicke, and Stu Milstein, the company emerged from stealth in October 2025 with a $21 million seed round, then closed a $39 million Series A in February 2026 led by EQT Dementia Fund and age1, bringing total funding to $60 million.

Alex Kaluzny

Paris, France · Person

Alex Kaluzny serves as Chief Technology Officer at Doctolib, one of Europe's foremost digital health unicorns, where he leads engineering and technical architecture for a platform used by over 80 million patients across France, Germany, and Italy. In this role he drives the company's technology strategy including its expansion into AI-assisted clinical tools and cross-border healthcare services. He is a prominent figure in the European health technology ecosystem and a recognised speaker on digital health innovation and enterprise technology at European policy forums.

Apex Ventures

Vienna, Austria · Venture Capital

Apex Ventures is a Vienna-based seed-stage venture capital firm launched in 2017 by Andreas Schwarzenbrunner, Wolfgang Berner, and Ulrich Gall, focused on deep tech, AI, medical devices, and digital health. The firm manages over EUR 50M and invests EUR 250K-1.5M in science-driven teams with defensible intellectual property, often emerging from leading European research institutions. Apex has backed companies including Prewave, Ribbonfish, and contextflow, and provides hands-on support in technology commercialization and clinical market access.

BrightCap Ventures

Sofia, Bulgaria · Venture Capital

Founded in 2018 by Georgi Mitov and Elina Halatcheva (joined by Managing Partner Diana Stefanova), BrightCap is a pre-seed and seed VC based in Sofia. Its second fund (BrightCap II) closed at approximately €47.5M in 2025, with the European Investment Fund as a cornerstone LP, and is notable as the first vehicle to blend Recovery and Resilience Facility capital from both Bulgaria and Romania in a single cross-border fund. Managing partners bring operating backgrounds from exits at VMware (Aviaso) and Honeywell (Sciant) rather than traditional finance. BrightCap invests €400K–€3M tickets with sector focus on future of work, digital health, and fintech; the portfolio includes Software Group, Pliant, and FITE.

Cathay Innovation

Paris, France · Venture Capital

Cathay Innovation is a Paris-headquartered global multi-stage venture capital firm founded in 2015, affiliated with Cathay Capital, with offices in San Francisco, Berlin, Madrid, Shanghai, and Singapore. The firm closed its third fund at $1 billion in 2025 — the largest AI-dedicated fund out of the European Union — bringing total assets under management to over €2.5 billion. Cathay invests in vertical AI, digital health, fintech, mobility, and energy across Europe, North America, and Asia, connecting startups with a corporate network of 20+ Fortune 500 partners. The portfolio of over 120 companies includes Glovo, Ledger, Owkin, Alma, and Descartes Underwriting, with eight unicorns, six IPOs, and 18 acquisitions.

Creathor Ventures

Zug, Switzerland · Venture Capital

Creathor Ventures is a pan-European venture capital firm founded over 30 years ago, managing more than €230 million across funds with offices in Bad Homburg and Zurich. The team has financed over 200 companies as lead or co-lead investors, with more than 20 portfolio companies reaching international stock exchanges. It focuses on deep tech and digital health, investing in areas such as AI, IoT, precision medicine, medtech, and cloud technology, primarily in Germany and Switzerland.

Crowberry Capital

Reykjavik, Iceland · Venture Capital

Crowberry Capital is a Nordic seed and early-stage venture fund founded in 2017 in Reykjavik, with additional offices in Copenhagen and Stockholm. The all-female founding team backs technology startups across the Nordics, with a particular focus on SaaS, digital health, fintech, and gaming. Its second fund closed at €90 million and the firm has invested in over 34 companies. Notable portfolio companies include Lucinity (AI anti-money laundering) and Mainframe Industries (cloud-native MMO gaming).

Dawn Health

Copenhagen, Denmark · Startup

Dawn Health develops regulated software-as-a-medical-device products with pharmaceutical and life-science partners. The company builds digital therapeutics and companion applications for adherence, remote monitoring, and real-world clinical data capture in regulated settings.

DMEA

Berlin, Germany · Event Organisator

Organizer of DMEA, Europe's leading digital health and healthcare IT trade fair held annually in Berlin. Drawing over 16,000 attendees and 700 exhibitors, DMEA showcases innovations in electronic health records, telemedicine, AI diagnostics, and hospital IT infrastructure, serving as a key meeting point for healthtech startups and health system leaders.

DMEA 2026

Berlin, Germany · Event

Europe's largest digital health trade fair at Messe Berlin, spanning healthcare IT, procurement, interoperability, and compliant medical software rollout. Includes the 'DMEA fuer Health Startups' program, the DMEA nova Award startup finals, and DMEA Sparks pitch visibility for early-stage health-tech companies.

Expon Capital

Luxembourg, Luxembourg · Venture Capital

Expon Capital is a Luxembourg-based venture capital firm founded in 2015 by Alain Rodermann, Jérôme Wittamer, Lily Wang, and Marc Gendebien. The firm has deployed over €90 million across 33 companies in 14 countries through successive Digital Tech Funds, with Fund IV planned for 2026. It backs seed and early-stage tech startups across cybersecurity, fintech, regtech, digital health, and edtech, with a particular focus on Luxembourg-origin companies. Notable portfolio successes include Salonkee, which grew to 250+ employees and raised a €28 million Series B led by PeakSpan Capital after Expon's initial investment.

FIRE1

Dublin, Ireland · Startup

FIRE1 is a Dublin-based medtech company developing the NORM heart failure management system, a remote monitoring implant designed to enable patients to control their fluid volume at home, similar to how continuous glucose monitors transformed diabetes care. The device received FDA Breakthrough Device Designation and has been successfully implanted in the first Irish patient at University Hospital Galway. FIRE1 has raised $210 million in total funding, including a $120 million round led by Polaris Partners and Elevage Medical Technologies.

Geneva Health Forum 2026

Geneva, Switzerland · Event

A biennial gathering at Campus Biotech, one of the largest global health conferences, bringing political, private, academic, and civil-society actors together on global health innovation and policy. For a healthtech founder in the Romandie it is the marquee venue to reach NGOs, multilateral health bodies, and impact funders.

Healee

Sofia, Bulgaria · Startup

Healee is a Sofia-based digital health company founded in 2017 by Hristo Kosev and Josif Dishliev. The platform enables healthcare organisations to manage provider scheduling, patient intake, and appointment workflows with support for virtual care models. Healee raised $2 million in 2022 to expand its telehealth solution into the US market and is backed by Eleven Ventures.

HLTH Europe

Amsterdam, Netherlands · Event Organisator

Organizer of HLTH Europe, a major health innovation conference connecting digital health startups with healthcare decision-makers in Amsterdam. Launched as the European sister event of the US-based HLTH conference, it brings together thousands of healthtech founders, hospital administrators, and investors to drive digital transformation in healthcare.

HomeDoctor

Warsaw, Poland · Startup

HomeDoctor is a Polish digital-health platform offering telemedicine consultations and in-home doctor visits across 30+ specialties. It runs a B2B model partnering with medical centres, insurers and employers to provide healthcare as a corporate benefit, with 200+ doctors serving patients nationwide.

Idoven

Madrid, Spain · Startup

Idoven is a Madrid-based digital health startup that uses AI to transform ECG analysis and cardiovascular diagnostics. Its Willem™ platform analyses 50,000 heartbeats in 60 seconds, identifying 86 electrical heart conditions that represent 90% of common cardiac problems — reaching 96.4% accuracy for atrial fibrillation detection. Founded in 2019 by Manuel Marina Breysse, José María Lillo Castellano, and Íñigo Juantegui, the company raised €18.5M Series A co-led by Insight Partners and Northzone with Wayra participation. Idoven operates B2B through hospitals, pharmaceutical trials, and healthcare systems, and employs 71 people as of early 2026.

Imprimatur Capital Fund Management

Riga, Latvia · Venture Capital

Imprimatur Capital Fund Management is a Riga-based early-stage venture capital firm founded in 2010 and affiliated with London-headquartered Imprimatur Capital Ltd. The firm manages seed and start-up funds backed by the Latvian Guarantee Agency and institutional investors, with over €17M under management and more than 70 portfolio companies. It targets B2B software, digital health, learning and training, and robotics startups at pre-Series A in the Baltic Sea Region. Key partners include Toby Moore (Managing Partner) and Jānis Janevičs (Partner).

Kilo Health

Vilnius, Lithuania · Startup

Kilo Health is a Vilnius-based digital health company founded in 2013 that builds, acquires, and scales a portfolio of 30+ health and wellness apps spanning weight management, fitness, mental health, chronic disease management, and personal care. The company serves over 7 million paying customers globally and employs 500+ people across Lithuania, Germany, and Latvia. Kilo Health operates as a health-app studio, applying performance marketing expertise and data-driven product iteration to grow individual apps rapidly. It is one of the largest and most profitable digital health companies in the Baltics, demonstrating Lithuania's strength in consumer app businesses.

Longenesis

Riga, Latvia · Startup

Longenesis is a Riga-based digital health company founded in 2017 that builds platforms connecting pharmaceutical companies, healthcare providers, and patients to accelerate biomedical research. Its three core products — Curator, Themis, and Engage — enable privacy-preserving patient cohort discovery, consent management, and real-world evidence generation. The company has positively impacted over 850,000 patients across the EU and MENA, holds partnerships with Medtronic and Novartis, and has raised over €1 million in seed funding. It won second place at the EIT Health Catapult programme and earned an AWS Industry Award in 2023.

Mangrove Capital Partners

Luxembourg, Luxembourg · Venture Capital

Mangrove Capital Partners is one of Europe's most storied early-stage venture capital firms, founded in Luxembourg in 2000 by Mark Tluszcz, Gerard Lopez, and Hans-Jürgen Schmitz. The firm manages over $1 billion in assets and has backed 8 unicorns, including Skype (a $2 million investment that returned $200 million) and Wix (an $8 million bet that returned $700 million). Mangrove invests at pre-seed and seed stage across Europe and Israel, with a team spanning Luxembourg, Berlin, Paris, Barcelona, and London. Portfolio companies include Flo Health, WalkMe, K Health, Talkwalker, and Doctena.

Materialise

Leuven, Belgium · Startup

Materialise is a pioneer in additive manufacturing, operating one of the world's largest 3D printing facilities alongside a suite of industrial and medical software. Its Mimics software suite supports surgical planning, personalised implants and medical device design for hospitals and MedTech firms globally; its industrial arm serves aerospace, automotive and consumer goods. Founded in 1990 in Leuven by Fried Vancraen and Hilde Ingelaere as the Benelux's first rapid-prototyping bureau, the company listed on NASDAQ (MTLS) in 2014. As of Q1 2026 it reported $302 M trailing revenue and a $335 M market cap, and in May 2026 spun off its eyewear division to focus on core manufacturing and healthcare software.

Nightingale Health

Helsinki, Finland · Startup

Nightingale Health is the global leader in NMR-based metabolomics, quantifying 250 blood biomarkers from a single sample to enable large-scale disease risk detection and prevention. Founded in Helsinki, it completed the analysis of all 500,000 UK Biobank samples, creating the world's largest blood biomarker database. Listed on Nasdaq Helsinki Main Market since March 2025, the company is deploying its technology into Finnish public healthcare in 2026 through wellbeing services counties. It also partnered with Alamar Biosciences to expand into brain health proteomics.

No Isolation

Oslo, Norway · Startup

No Isolation is a Norwegian scale-up founded in 2015 that develops telepresence robots to combat social isolation. Its flagship product, the AV1 robot, serves as a physical avatar in classrooms for children with long-term illness or special education needs, keeping them connected to school and peers when they cannot attend. The company now serves over 900 customers across 19 countries with more than 3,000 AV1 units deployed in around 2,500 schools, supporting over 10,000 children. No Isolation won the 2025 EURORDIS Company Award for Health Technology.

Nobi

Antwerp, Belgium · Startup

Nobi makes AI-powered smart ceiling lamps for senior living facilities that detect falls within seconds, alert caregivers instantly and monitor sleep, activity and circadian patterns to prevent incidents. Its model was trained on 250,000+ real-life fall scenarios; in clinical studies across five care homes, Nobi reduced average caregiver response time from over one hour to four minutes and cut falls by 51%. Founded in 2018 in Antwerp by Roeland Pelgrims, Bert De Haes and Stijn Verrept, it closed a €35 M Series B (co-led by Angelini Ventures and Nexus NeuroTech) in January 2025. Nobi is deployed in 22 countries with offices in Belgium, the US and the UK.

Oviva

Zurich, Switzerland · Startup

Oviva is a digital health company that helps people with weight-related and metabolic conditions, including obesity, type 2 diabetes, prediabetes, and hypertension, improve their health through medical nutritional therapy. Its model combines a medical-device-certified smartphone app with clinical teams of doctors, dietitians, and behavioural specialists, with patients logging meals, activity, and weight while receiving tailored remote support from their dietitian. The company describes itself as Europe's leading digital health provider for weight-related conditions, with care reimbursed as a certified DiGA in Germany, delivered in partnership with the NHS in the UK, and integrated into Swiss public healthcare. It is headquartered in Zurich.

Redalpine

Zurich, Switzerland · Venture Capital

Redalpine is a Zurich-based multi-stage venture capital firm founded in 2006 by Michael Sidler and Peter Niederhauser, and has grown into one of the most active Swiss VCs by number of early-stage checks across the DACH and wider European technology landscape. The firm invests from seed through Series B across digital health, fintech, deep tech, climate tech, and software, and is best known as an early backer of N26, Taxfix, Inkitt, 9fin, and Proxima Fusion. Redalpine closed its sixth fund at EUR 300+ million in 2023 and has built one of the larger Swiss-based venture teams, typically writing checks between EUR 1-15 million into companies it then follows through multiple rounds. It is a reference fund for Swiss and DACH founders looking for a locally anchored lead investor with international reach.

RTA Ventures

Warsaw, Poland · Accelerator

Founded 2011. Early-stage investor focused on digital health, telemedicine, and SaaS. RTA Ventures is an accelerator programme based in Warsaw, Poland. The programme supports startups in Digital Health, Telemedicine, SaaS.

Swisscom Ventures

Bern, Switzerland · Venture Capital

Swisscom Ventures is the strategic corporate venture arm of Swisscom, Switzerland's largest telecom and ICT operator, and is one of the most active corporate venture investors in the Swiss ecosystem. Founded in 2007 and operating with offices in Bern, Zurich, and Silicon Valley, the firm invests in early- and growth-stage technology companies across cybersecurity, digital health, cloud infrastructure, AI, and network-adjacent deep tech, with particular interest in startups that can leverage Swisscom's distribution, data, or network assets. Portfolio companies have included Cato Networks, Mirakl, Scandit, Digital Asset, and Exeger. Swisscom Ventures pairs well with the traditional Swiss financial-VC bench by providing strategic commercial partnerships, regulatory navigation, and European telecom channel access alongside capital, which is particularly valuable for founders in regulated infrastructure categories.

Sword Health

Porto, Portugal · Startup

Sword Health is a Portuguese digital health company focused on musculoskeletal care delivered through a mix of sensors, software, and remote clinical support. The company became prominent by showing that physical therapy does not need to depend entirely on repeated in-person visits when patient motion can be measured remotely and paired with continuous guidance from licensed professionals. Its model combines wearable motion tracking, AI-assisted feedback, and human clinicians into a structured care program that large employers and health plans can offer at scale. That makes Sword Health more than a telehealth app; it is a vertically integrated care-delivery product with hardware, data, and clinical workflow built together. In the European startup ecosystem, Sword Health is a strong example of how deep health-tech products can emerge from the region and sell into highly demanding enterprise buyers in healthcare and HR. It also broadens the directory's coverage of sensor-driven health platforms by linking medical use cases with the kinds of product, data, and device capabilities that have made other European health companies successful.

UMNAI

Ta' Xbiex, Malta · Startup

UMNAI is a Malta-based deep-tech AI company founded in 2019 by Dr. Angelo Dalli and Ken Cassar. The company has developed a neuro-symbolic Hybrid Intelligence framework that combines neural networks with symbolic reasoning, enabling AI systems to make consequential decisions that are explainable, auditable, and compliant with EU AI regulation. UMNAI's technology is deployed in financial services, healthcare, insurance, and justice, where regulatory accountability is non-negotiable. The company has been granted 30 patents with a further 22 pending, and Cassar represents Malta at the CEN/CENELEC JTC 21 AI standards committee.

Whereby

Oslo, Norway · Startup

Whereby is an Oslo-based video communication platform founded in 2013 (originally as appear.in inside Telenor). It offers browser-based video meetings requiring no downloads or guest logins, and a developer-facing Whereby Embedded API for adding video calling to third-party products. GDPR-compliant and ISO 27001 certified, the platform supports healthcare, telehealth and education use cases. The company raised $12 million in Series A funding from Point Nine and SaaStr in 2021 and saw a 450% user surge during the pandemic, with adoption across 150 countries.