Luxembourg City, Luxembourg · Startup Doctena is a Luxembourg-based healthtech platform that enables patients to book medical appointments online across multiple European countries. The system connects patients with doctors, dentists, and specialists through a unified booking interface while providing healthcare practitioners with schedule management, patient communication, and practice administration tools. Operating across Luxembourg, Belgium, the Netherlands, Germany, and Austria, Doctena has become one of the leading medical appointment platforms in the Benelux region and a key example of how healthtech can scale across fragmented European healthcare systems.
Startup Growth HealthTechMarketplaceB2B SaaS
Luxembourg City, Luxembourg · Startup Luxembourg-based digital platform for company incorporation and accounting. Enables entrepreneurs to register a SARL or SARL-S 100% online in five days with no paperwork, paired with a smart accounting dashboard for VAT tracking, invoicing, and expense management from €90/month. Designed by Luxembourg fiduciary professionals.
Startup LegalTechB2B SaaSFintech
Luxembourg City, Luxembourg · Startup Luxembourg-based AI company specialising in neural network compression and optimisation for autonomous driving and computer vision applications. Its technology maintains model accuracy while dramatically reducing power consumption and inference costs, enabling deployment of advanced AI on edge devices in vehicles and robotics.
Startup AIDeep Tech
Luxembourg City, Luxembourg · Startup Luxembourg-based social-impact startup using AI and positive psychology to build youth mental resilience. Its tools are designed for schools, families, and public health agencies to provide preventive mental-health education for children. Named among the Global Top 30 AI Impact Solutions at the AI Impact Summit 2026. Founded by Luanna Eroles.
Startup Pre-Seed EdTechHealthTechAI
Luxembourg City, Luxembourg · Startup Job Today is a Luxembourg-registered mobile-first hiring platform focused on the hourly-and-service segment of the labor market — retail, hospitality, warehouses, logistics, beauty, care — where traditional job boards like LinkedIn and Indeed have always been an awkward fit. The product lets candidates build a one-tap profile, browse open roles around their location, and chat directly with employers inside the app, effectively turning the recruiting process into a messaging experience closer to Tinder or WhatsApp than a legacy ATS. Founded by Polina Montano and Eugene Mizin in 2015, the company raised over USD 35 million from investors including Accel and Mangrove Capital Partners and operates primarily in the UK and Spain. Job Today is one of the more visible consumer-facing tech companies headquartered out of Luxembourg and a useful example of how the country's legal and corporate infrastructure attracts startups far beyond pure finance.
Startup Growth HR TechConsumer AppsHiringMarketplace
Luxembourg City, Luxembourg · Startup Kneip is a Luxembourg-founded investment-data and fund-reporting company that sits in the plumbing between asset managers, fund domiciles, and the distribution channels (banks, platforms, regulators) where funds are actually sold. For decades it has been one of the largest providers of European fund data dissemination, handling NAVs, KIIDs/PRIIPs KIDs, MiFID II data templates, and regulatory reporting packages for hundreds of asset managers — unglamorous but absolutely load-bearing infrastructure for the EUR 5-trillion-plus Luxembourg fund industry. In 2022 Kneip was acquired by Deutsche Börse and integrated into the group's data-services business, effectively turning a Luxembourg-grown fund-tech operator into part of a top-tier European exchange's data franchise. It is a clean example of how Luxembourg's tax and legal specialization in funds translates into globally relevant software companies that outsiders rarely hear about.
Startup Growth FintechAsset ManagementData ServicesRegTech
Luxembourg City, Luxembourg · Startup A University of Luxembourg spinoff founded in 2016 by researchers Pouyan Ziafati and Aida Nazarikhorram. LuxAI develops the QTrobot, a 60 cm humanoid social robot designed to support therapists and educators working with children who have autism or special educational needs. The robot is assembled in Luxembourg and sold in over 25 countries across Europe, Asia, and North America.
Startup Growth Social RoboticsEdTechHealth Tech
Luxembourg City, Luxembourg · Startup Luxhub is a Luxembourg-based open banking infrastructure provider that builds API connectivity between banks, fintechs, and third-party providers under PSD2 and open finance regulations. The platform enables account information services, payment initiation, and data-sharing workflows that allow financial institutions to comply with regulatory requirements while also opening new distribution channels for fintech products. Founded with backing from four major Luxembourg banks, Luxhub is a strategically important piece of the country's financial innovation infrastructure and a model for how collaborative banking initiatives can accelerate open finance adoption across Europe.
Startup Growth FintechOpen BankingAPI Infrastructure
Luxembourg City, Luxembourg · Startup LuxTrust is the Luxembourg public-private joint venture that runs the country's national digital-identity and qualified electronic-signature infrastructure, and is effectively the backbone that lets Luxembourgish citizens, banks, and corporates sign contracts, file taxes, and access sensitive public services online with legally binding eIDAS-qualified signatures. Founded in 2005 and co-owned by the Luxembourg state alongside most of the country's major banks, LuxTrust has become one of the largest qualified trust service providers in the EU and one of the reference implementations of how an EU member state can stand up an interoperable, bank-grade identity layer ahead of the upcoming European Digital Identity Wallet (EUDI Wallet) rollout. For the directory, LuxTrust is a rare example of a core sovereign-tech asset that has the commercial surface area of a scale-up, and a useful anchor for understanding Luxembourg's outsized role in European digital-identity and regtech.
Startup Growth Digital IdentityTrust ServicesRegTechCybersecurity
Esch-sur-Alzette, Luxembourg · Startup A Luxembourg deep-tech startup founded in 2018 by a team with backgrounds in ESA space missions. Maana Electric builds the TerraBox, a mobile factory that produces solar panels from sand and electricity using in-situ resource utilisation (ISRU) technology. The company signed a multi-million-euro contract with the European Space Agency in 2021 and received first commercial orders worth €100 million in 2023. Its LunaBox variant is designed to manufacture solar panels and generate oxygen on the Moon.
Startup Growth Space TechClean EnergyDeep Tech
Luxembourg City, Luxembourg · Startup Luxembourg-based AI platform enabling direct-to-consumer brands to expand across global marketplaces by automating inventory management, pricing, marketing, logistics, compliance, and fulfilment. Founded by ex-Amazon executives in 2022. Raised $8M Series A from Expon Capital and Smedvig Ventures.
Startup Series A AIE-commerceB2B SaaS
Luxembourg City, Luxembourg · Startup Luxembourg-based privacy-first social network designed as a European alternative to algorithm-driven platforms. Offers chronological feeds, no behavioural tracking, no AI-generated content, and a distance feature letting users control how far their posts travel. Subscription model (€2.95–5.95/month). Raised €655K pre-seed from European investors. 36,000 early-access users.
Startup Pre-Seed Social MediaConsumer Tech
Luxembourg City, Luxembourg · Startup Luxembourg-based fintech providing SPARK, an AI-powered operating ecosystem for automating investment operations in asset management. Handles middle- and back-office oversight with agentic AI, processing 5 petabytes of data monthly for institutions including BNP Paribas Securities Services, Amundi, and Capital Group across €500bn+ in assets.
Startup FintechAIB2B SaaS
Luxembourg City, Luxembourg · Startup SaaS Group is a Luxembourg-based acquirer and operator of bootstrapped B2B SaaS businesses, founded with the goal of providing founder-friendly exits for software companies between $1 million and $10 million in ARR. The group currently operates 18 portfolio companies spanning online marketing, productivity, and developer tools, with combined annual recurring revenue exceeding $60 million and teams spread across 33 countries. It distinguishes itself by preserving the autonomy and culture of acquired companies while providing shared functions in marketing, finance, and HR.
Startup SaaSHolding
Luxembourg City, Luxembourg · Startup A Luxembourg-based RegTech company founded in 2015 by Pierre Gerard and Laurent Kratz, specialising in blockchain analytics and AML/CFT compliance for digital assets. Its platform monitors transactions across 21+ blockchains and serves over 200 clients in more than 40 countries, including exchanges, custodians, banks, and regulators. Clients include PwC and Swisscom, and the company raised a pre-Series A round backed by Tioga Capital and CV VC.
Startup Series A RegTechBlockchainCompliance
Luxembourg City, Luxembourg · Startup The European headquarters of Spire Global (founded 2012, originally San Francisco), established in Luxembourg City in 2017 with backing from the Luxembourg Future Fund. Spire operates one of the world's largest commercial nanosatellite constellations — over 110 CubeSats — collecting maritime, aviation, and weather data sold as space-to-cloud analytics. Luxembourg is home to Spire's maritime data team and served as the anchor for a $70 million Series C round led by the Luxembourg government.
Startup Public Space TechData AnalyticsMaritimeWeather
Luxembourg City, Luxembourg · Startup A Luxembourg-headquartered digital securities marketplace founded in 2018 by Arnab Naskar, Tobias Seidl, and Lennart Ante. STOKR operates an EU-regulated issuance platform for security tokens built on Bitcoin's Liquid Network, serving both professional and retail investors. The company is registered as a VASP with the CSSF and surpassed $1 billion in tokenised asset volume by 2025.
Startup Growth FintechBlockchainCapital Markets
Luxembourg City, Luxembourg · Startup Talkwalker is a Luxembourg-based social intelligence and consumer analytics platform that helps enterprises monitor and interpret public digital conversation at large scale. The product ingests data from social media, online news, forums, blogs, and other public sources, then applies AI and language processing to identify trends, sentiment shifts, competitive movement, and brand reputation risks. This makes it valuable for communications, marketing, and product teams that need external market signal rather than only internal customer data. In the European startup ecosystem, Talkwalker is important because it turns large volumes of messy unstructured internet data into decision-support infrastructure for major companies. It also complements internal governance and analytics platforms by focusing on what organizations can learn from the outside world in real time. For this directory, Talkwalker helps extend coverage into social intelligence and brand analytics, a category that sits between data infrastructure, marketing strategy, and customer insight.
Startup Growth Social IntelligenceData AnalyticsAI
Luxembourg City, Luxembourg · Startup A Luxembourg fintech founded in 2017 by Luc Falempin and Daniel Coheur that provides an institutional-grade, no-code tokenisation platform for the issuance, transfer, and lifecycle management of digital securities on public blockchains. The company's T-REX (Token for Regulated EXchanges) open standard enables compliance-native security tokens. Tokeny tokenised over €28 billion in assets between 2017 and 2023 and was acquired by Apex Group in May 2025.
Startup Acquired FintechBlockchainAsset Management
Luxembourg City, Luxembourg · Startup Luxembourg deep-tech startup developing heated polymer filaments using advanced nanocomposite materials for surface heating applications in electric vehicles and smart buildings. Its ultra-thin conductive wire enables efficient in-cabin and battery heating for EVs, reducing range loss in cold weather. Founded in 2022 by Vlad Batkhin.
Startup Deep TechCleanTech